Shree Ganesh Group

Reasons to Use Thionyl Chloride for Chlorination in Pharmaceutical Industries

Global thionyl chloride consumption market is segmented on the basis of product type, application, and geography. It is a useful compound in chemical reactions, but is very toxic and dangerous. It is a source of chloride ions, which plays the big role in pharmaceutical industry as a chlorinating agent. For environmental protection, Shree Ganesh Remedies Limited conveys chlorination reagents in closed systems. Gaseous by-products from the chlorination processes are recycled and or converted into suitable secondary products which can be sold in to market.

  1. Thionyl chloride has a relative density of 1.676 and melting point of -104.5ºC. It is easily decomposed into hydrogen chloride and sulfur dioxide.
  2. It is used for the production of isocarbophos, indomethacin, vitamin A, sumicidin, propargite tetramisole hydrochloride, and so on.
  3. It is also used as the chlorinating agents for organic synthesis such as chlorination of alcoholic group, chlorination of acid anhydride, chlorination of carboxylic acid, and the chlorine displacement of organic sulfonic acid or carboxylic acid.

The Benefits of Chlorination in Pharmaceuticals

  1. Backward integration into reagents
  2. Sustainable production processes
  3. Efficient chlorination in batch and continuous processes
  4. Environmentally friendly recycling of sidestreams

Thionyl Chloride as Chlorinating Agent

It can be used as the chlorinating agents for organic synthesis such as chlorination of alcoholic hydroxyl group, chlorination of carboxylic acid, chlorination of acid anhydride and the chlorine displacement of organic sulfonic acid or carboxylic acid.

Why Thionyl chloride is better than Other Chlorinating Agents?

Compared with other agents, Thionyl chloride is often the preferred reagents, because both the reaction product of sulfur dioxide and hydrogen chloride are gaseous and is easily to be separated. The excess amount of Thionyl chloride can be removed by distillation. Thionyl chloride is used in the preparation of following products,

4-Chlorobutyryl Chloride,

3-(Dibutylamino) Propyl Chloride Hydrochloride

ChloroAlkyl Amine’s and more

Wrapping Up

Chlorination using Thionyl Chloride is the core expertise at Shree Ganesh Remedies Limited. They have its own manufacturing, research and quality control facilities at one place. They utilize the reaction technologies for customized reactions for complicated processes and advanced pharmaceuticals. They are expertise at doing Chlorination using Thionyl Chloride though Thionyl Chloride being very corrosive and very hazardous.

They offer custom chlorination reactions within its integrated manufacturing system, in which off-gases are separated, purified and returned to the system as feedstocks. This permits sustainable production from pilot quantities to large commercial volumes using both batch and continuous processes. This increases yield and purity and reduces the proportion of unwanted secondary products.

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